Outside of Normal Limits: False Positive/Negative Anti TG2 Autoantibodies

Origins of anti-DNA autoantibodies.

Intricacies of anti-DNA autoantibodies.

Isotypes of anti-islet autoantibodies.

151 I n this issue of Diabetes Care, Hawa et al. (1) conclude that " the pathogenesis of antigen-specific antibodies in type 1 diabetes and type 2 diabetes is similar and p robably involves a chronic nonrandom antigen-driven polyclonal B-cell activation that is consistent with a Th1-type immune response. " The data presented also indicate that what are now standard anti-islet autoantibody assay...

Anti-Human Cardiac Myosin Autoantibodies

Human Anti-p68 Autoantibodies Recognize

Autoimmune phenomenaare known to occur in a large variety of human diseases (for review see reference 1) . Antibodies to self-components (autoantibodies) can be directed against organ-specific or non-organ-specific target structures and can develop transiently or persist chronically. Some are regarded as diagnostic markers for certain diseases, and some are pathogenic or contribute to disease d...